FOUNDATIONAL TERM
epigenetics
表观遗传
The study of regulatory changes affecting gene activity without altering the DNA base sequence.
Study this concept in context
04 · Genes and Environment: Why People Differ
Relatives may resemble one another and share a history of illness, yet their health can follow different paths. Understanding why requires us to distinguish DNA sequence, gene expression, environmental influences, and the probability of disease.
Sources
- NHGRI: Gene Expression
- NHGRI: Mutation
- MedlinePlus Genetics: Phenylketonuria
- MedlinePlus Genetics: Complex Disorders
- MedlinePlus Genetics: Penetrance and Expressivity
- NHGRI: Epigenomics Fact Sheet
Definitions come from the published lessons. Read the linked lesson for mechanisms, conditions and examples.