FOUNDATIONAL TERM
surrogate endpoint
替代终点
An indicator used in place of a clinical outcome with context-specific supporting evidence.
Study this concept in context
81 · Comparing treatments and personal preferences
Comparing treatments means asking which outcomes an option improves, over what period and at what burden, and whether those outcomes fit the person’s goals. Mechanisms, research, and values contribute to a decision that can be reviewed.
Sources
- AHRQ: The SHARE Approach
- FDA: Surrogate endpoints
- Smart Health Choices: Absolute and relative risk
- FDA: Managing benefits and risks of medicines
- NCI: How clinical trials work
- MedlinePlus: Evaluating health information
Definitions come from the published lessons. Read the linked lesson for mechanisms, conditions and examples.